Loci by Analysis of VDJ Gene Immunoglobulin H Chain V Region Gene The Inference of Phased Haplotypes for the

نویسندگان

  • Mark M. Tanaka
  • Bruno A. Gaëta
  • Andrew M. Collins
  • Scott D. Boyd
  • Andrew Z. Fire
  • Marie J. Kidd
  • Zhiliang Chen
  • Yan Wang
چکیده

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منابع مشابه

The inference of phased haplotypes for the immunoglobulin H chain V region gene loci by analysis of VDJ gene rearrangements.

The existence of many highly similar genes in the lymphocyte receptor gene loci makes them difficult to investigate, and the determination of phased "haplotypes" has been particularly problematic. However, V(D)J gene rearrangements provide an opportunity to infer the association of Ig genes along the chromosomes. The chromosomal distribution of H chain genes in an Ig genotype can be inferred th...

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Cloning and expression of the constant region of rainbow trout (Onchorhynchus mykiss) µ immunoglobulin chain in Escherichia coli

The importance of rainbow trout (Onchorhynchus mykiss) in Iran aquaculture industry on one hand, and increasing the mortality of this fish due to outbreaks of infectious diseases, on the other hand, indicate the requirement for more profound understanding the rainbow trout immune system and access to laboratory tools for definitive diagnosis of its diseases. One of the most important defense me...

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تاریخ انتشار 2011